Research workbench

Hydrolysis of GTP to GDP by an mcm-associated and meab- and mmaa-like G-protein from mycobacterium tuberculosis

Analyse Hydrolysis of GTP to GDP by an mcm-associated and meab- and mmaa-like G-protein… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3P32
Type: protein
Length: 306 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Probable GTPase RV1496/MT1543
EC: 3.6.-.-
UniProt: P63577
Ligands: GDP
Pockets: 4 · best druggability 0.53

Structure

x-ray diffraction · 1 distinct chain · 58% helix, 13% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Probable GTPase RV1496/MT1543 (EC 3.6.-.-)	protein	306	58% helix, 13% strand	P63577

Ligands and binding sites

GDP · Guanosine-5'-diphosphate · ligand · chains A
PGE · Triethylene glycol · additive · 2 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	185	0.53	0.78	24	empty
2	115	0.35	0.73	17	PGE
3	68	0.32	0.75	14	empty
4	50	0.30	0.76	14	empty

Compared structures

3P32 · Hydrolysis of GTP to GDP by an MCM-associated and MeaB- and MMAA-like G-protein from… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P63577
Elsewhere: RCSB PDB 3P32 · PDBe 3P32 · UniProt P63577

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.