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The crystal structure of enterotoxigenic escherichia COLI gspc-gspd complex from the type II secretion system

Analyse The crystal structure of enterotoxigenic escherichia COLI gspc-gspd complex… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
3OSS
Type
protein
Length
222 residues
Chains
2
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Type 2 secretion system, gspc; Type 2 secretion system, secretin gspd
UniProt
E3PJ87, E3PJ86
Ligands
CA, CL

Structure

x-ray diffraction · 2 distinct chains · 27% helix, 41% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
CType 2 secretion system, gspcprotein650% helix, 58% strandE3PJ87
DType 2 secretion system, secretin gspdprotein15739% helix, 34% strandE3PJ86

Ligands and binding sites

  • CA · Calcium ion · metal · chains D
  • CL · Chloride ion · ion · chains D

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

1 interface between chains.

  • C–D · 671 Ų buried · 11 hydrogen bonds · protein-protein

Compared structures

  • 3OSS · The crystal structure of enterotoxigenic Escherichia coli GspC-GspD complex from the type… · the same entry in another collection · chain C against C, TM-score 1.00
  • E3PJ87 · AlphaFold monomer V2.0 prediction for type II secretion system protein C 2 (E3PJ87) · a predicted model of the same protein · chain C against A, TM-score 0.97
  • E3PJ86 · AlphaFold monomer V2.0 prediction for secretin gspd 2 (E3PJ86) · a predicted model of the same protein · chain D against A, TM-score 0.49

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