Research workbench

Structure of linb complexed with 1,2-dichloroethane

Analyse Structure of linb complexed with 1,2-dichloroethane in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1G5F
Type: protein
Length: 294 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: 1,3,4,6-tetrachloro-1,4-cyclohexadiene hydrolase
EC: 3.8.1.-
UniProt: P51698
Ligands: DCE, CA, CL
Pockets: 2 · best druggability 0.70

Structure

x-ray diffraction · 1 distinct chain · 43% helix, 20% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	1,3,4,6-tetrachloro-1,4-cyclohexadiene hydrolase (EC 3.8.1.-)	protein	294	43% helix, 20% strand	P51698

Ligands and binding sites

DCE · 1,2-dichloroethane · ligand · chains A
CA · Calcium ion · metal · 3 copies · chains A
CL · Chloride ion · ion · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	57	0.70	0.97	19	CL, DCE
2	66	0.37	0.78	16	empty

Modifications

Observed in the structure: 1 modified (methylation).

Compared structures

1G5F · Structure of linb complexed with 1,2-dichloroethane · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P51698
Elsewhere: RCSB PDB 1G5F · PDBe 1G5F · UniProt P51698

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.