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Crystal structure of human HIWI1 paz domain (residues 277-399) in complex with 14-mer RNA (12-bp + 2-nt overhang) containing 2'-oh at its 3'-end
Analyse Crystal structure of human HIWI1 paz domain (residues 277-399) in complex with… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3O3I
- Type
- protein + RNA
- Length
- 122 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Piwi-like protein 1; RNA (5'-R(*GP*CP*GP*AP*AP*UP*AP*UP*UP*CP*GP*CP*UP*U)-3')
- UniProt
- Q96J94
Structure
x-ray diffraction · 2 distinct chains · 27% helix, 24% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| X | Piwi-like protein 1 | protein | 108 | 27% helix, 24% strand | Q96J94 |
| A | RNA (5'-R(*GP*CP*GP*AP*AP*UP*AP*UP*UP*CP*GP*CP*UP*U)-3') | rna | 14 | — | — |
Interfaces
1 interface between chains.
- X–A · 468 Ų buried · 13 hydrogen bonds · protein-nucleic
Compared structures
- 3O3I · Crystal Structure of human Hiwi1 PAZ domain (residues 277-399) in complex with 14-mer RNA… · the same entry in another collection · chain A against A, TM-score 1.00
- Q96J94 · AlphaFold monomer V2.0 prediction for piwi-like protein 1 (Q96J94) · a predicted model of the same protein · chain X against A, TM-score 0.92
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q96J94
- Elsewhere: RCSB PDB 3O3I · PDBe 3O3I · UniProt Q96J94
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