MolNFT v1 · #300347 · protein
AlphaFold monomer V2.0 prediction for piwi-like protein 1 (Q96J94)
Q96J94: “AlphaFold monomer V2.0 prediction for piwi-like protein 1 (Q96J94)”. 10 pockets (best druggability 0.79). MolNFT v1 #300347 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q96J94
- Type
- protein
- Length
- 861 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x40B9C9d5F084D34d026E9d5Dd10501AcdF6d6152
- Molecule
- Piwi-like protein 1
- UniProt
- Q96J94
- Pockets
- 10 · best druggability 0.79
Structure
1 distinct chain · 29% helix, 26% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Piwi-like protein 1 | protein | 861 | 29% helix, 26% strand | Q96J94 |
Pockets
10 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 524 | 0.79 | 0.86 | 73 | empty |
| 2 | 213 | 0.69 | 0.86 | 31 | empty |
| 3 | 86 | 0.58 | 0.87 | 20 | empty |
| 4 | 70 | 0.54 | 0.87 | 17 | empty |
| 5 | 52 | 0.38 | 0.80 | 14 | empty |
Compared structures
- 2L5C · Solution structures of human piwi-like 1 paz domain · an experimental structure of the same protein · chain A against A, TM-score 0.13
- 2L5C · Solution structures of human PIWI-like 1 PAZ domain · an experimental structure of the same protein · chain A against A, TM-score 0.13
- 2L5D · Solution structures of human piwi-like 1 paz domain with ssrna (5'- pugaca) · an experimental structure of the same protein · chain A against A, TM-score 0.13
- 2L5D · Solution Structures of human PIWI-like 1 PAZ domain with ssRNA (5'-pUGACA) · an experimental structure of the same protein · chain A against A, TM-score 0.13
- 3O3I · Crystal structure of human HIWI1 paz domain (residues 277-399) in complex with 14-mer RNA… · an experimental structure of the same protein · chain A against X, TM-score 0.12
- 3O3I · Crystal Structure of human Hiwi1 PAZ domain (residues 277-399) in complex with 14-mer RNA… · an experimental structure of the same protein · chain A against X, TM-score 0.12
- 3O6E · Crystal Structure of human Hiwi1 PAZ domain (residues 277-399) in complex with 14-mer RNA… · an experimental structure of the same protein · chain A against X, TM-score 0.12
- 3O6E · Crystal structure of human HIWI1 paz domain (residues 277-399) in complex with 14-mer RNA… · an experimental structure of the same protein · chain A against X, TM-score 0.12
- 3O7V · Crystal structure of human HIWI1 (V361M) paz domain (residues 277-399) in complex with… · an experimental structure of the same protein · chain A against X, TM-score 0.12
- 3O7V · Crystal Structure of human Hiwi1 (V361M) PAZ domain (residues 277-399) in complex with… · an experimental structure of the same protein · chain A against X, TM-score 0.12
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q96J94
- Elsewhere: UniProt Q96J94 · AlphaFold DB Q96J94
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