Research workbench

Structure of the (SR)CA2+-ATPase CA2-E1-caamppcp form

Analyse Structure of the (SR)CA2+-ATPase CA2-E1-caamppcp form in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3N8G
Type: protein
Length: 994 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: SARCOPLASMIC/ENDOPLASMIC reticulum calcium ATPase 1 isoform serca 1A
EC: 3.6.3.8
UniProt: B6CAM1
Ligands: ACP, CA, K
Pockets: 20 · best druggability 0.85

Structure

x-ray diffraction · 1 distinct chain · 46% helix, 16% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	SARCOPLASMIC/ENDOPLASMIC reticulum calcium ATPase 1 isoform serca 1A (EC 3.6.3.8)	protein	994	46% helix, 16% strand	B6CAM1

Ligands and binding sites

ACP · Phosphomethylphosphonic acid adenylate ester · ligand · chains A
CA · Calcium ion · metal · 3 copies · chains A
K · Potassium ion · metal · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

20 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	926	0.85	0.87	104	CA, ACP
2	345	0.74	0.86	47	empty
3	329	0.69	0.83	39	empty
4	504	0.67	0.78	50	empty
5	322	0.60	0.78	32	empty

Compared structures

3N8G · Structure of the (SR)Ca2+-ATPase Ca2-E1-CaAMPPCP form · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt B6CAM1
Elsewhere: RCSB PDB 3N8G · PDBe 3N8G · UniProt B6CAM1

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.