Research workbench
Crystal structure of the chromodomain-ATPase portion of the yeast CHD1 chromatin remodeler
Analyse Crystal structure of the chromodomain-ATPase portion of the yeast CHD1… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3MWY
- Type
- protein
- Length
- 696 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Chromo domain-containing protein 1
- EC
- 3.6.1.-
- UniProt
- P32657
- Ligands
- AGS
- Pockets
- 14 · best druggability 0.79
Structure
x-ray diffraction · 1 distinct chain · 41% helix, 14% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| W | Chromo domain-containing protein 1 (EC 3.6.1.-) | protein | 696 | 41% helix, 14% strand | P32657 |
Ligands and binding sites
- AGS · Phosphothiophosphoric acid-adenylate ester · ligand · chains W
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
14 pockets found on a 1 Å grid, 7 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 199 | 0.79 | 0.93 | 36 | empty |
| 2 | 764 | 0.70 | 0.77 | 53 | AGS |
| 3 | 62 | 0.63 | 0.92 | 15 | empty |
| 4 | 139 | 0.63 | 0.86 | 23 | empty |
| 5 | 333 | 0.62 | 0.79 | 35 | empty |
Compared structures
- 3MWY · Crystal structure of the chromodomain-ATPase portion of the yeast Chd1 chromatin remodeler · the same entry in another collection · chain W against W, TM-score 1.00
- P32657 · AlphaFold monomer V2.0 prediction for chromo domain-containing protein 1 (P32657) · a predicted model of the same protein · chain W against A, TM-score 0.68
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P32657
- Elsewhere: RCSB PDB 3MWY · PDBe 3MWY · UniProt P32657
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