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Small subunit (R2F) of native ribonucleotide reductase from corynebacterium ammoniagenes

Analyse Small subunit (R2F) of native ribonucleotide reductase from corynebacterium… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3MJO
Type: protein
Length: 592 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Ribonucleotide reductase subunit R2F
UniProt: O69274
Ligands: MN3
Pockets: 5 · best druggability 0.44

Structure

x-ray diffraction · 1 distinct chain · 78% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Ribonucleotide reductase subunit R2F	protein	296	78% helix, 0% strand	O69274

Ligands and binding sites

MN3 · Manganese (III) ion · metal · 4 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

5 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	164	0.44	0.74	26	empty
2	124	0.40	0.75	19	empty
3	57	0.32	0.76	16	empty
4	54	0.31	0.76	16	empty
5	53	0.28	0.74	12	empty

Interfaces

1 interface between chains.

A–B · 2747 Å² buried · 26 hydrogen bonds · protein-protein

Compared structures

3MJO · Small subunit (R2F) of native ribonucleotide reductase from Corynebacterium ammoniagenes · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O69274
Elsewhere: RCSB PDB 3MJO · PDBe 3MJO · UniProt O69274

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