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Crystal structure of human NUDT16

Analyse Crystal structure of human NUDT16 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3MGM
Type: protein
Length: 328 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: U8 snorna-decapping enzyme
EC: 3.6.1.-
UniProt: Q96DE0
Pockets: 3 · best druggability 0.73

Structure

x-ray diffraction · 1 distinct chain · 30% helix, 32% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	U8 snorna-decapping enzyme (EC 3.6.1.-)	protein	164	30% helix, 32% strand	Q96DE0

Pockets

3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	76	0.73	0.97	21	empty
2	158	0.49	0.78	31	empty
3	149	0.47	0.77	26	empty

Interfaces

1 interface between chains.

A–B · 1366 Å² buried · 16 hydrogen bonds · protein-protein

Compared structures

3MGM · Crystal structure of human NUDT16 · the same entry in another collection · chain A against A, TM-score 1.00
Q96DE0 · AlphaFold monomer V2.0 prediction for U8 snorna-decapping enzyme (Q96DE0) · a predicted model of the same protein · chain A against A, TM-score 0.94

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q96DE0
Elsewhere: RCSB PDB 3MGM · PDBe 3MGM · UniProt Q96DE0

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