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Crystal structure of ARGININE/ORNITHINE transport system ATPase from mycobacterium tuberculosis bound to GDP (a RAS-like GTPase superfamily protein)

Analyse Crystal structure of ARGININE/ORNITHINE transport system ATPase from… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3MD0
Type: protein
Length: 301 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: ARGININE/ORNITHINE transport system ATPase
UniProt: P63577
Ligands: GDP, UNX
Pockets: 4 · best druggability 0.55

Structure

x-ray diffraction · 1 distinct chain · 58% helix, 12% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	ARGININE/ORNITHINE transport system ATPase	protein	301	58% helix, 12% strand	P63577

Ligands and binding sites

GDP · Guanosine-5'-diphosphate · ligand · chains A
UNX · Unknown atom or ion · ion · 4 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	187	0.55	0.79	24	empty
2	166	0.45	0.75	21	empty
3	79	0.33	0.75	15	empty
4	67	0.30	0.74	13	empty

Compared structures

3MD0 · Crystal structure of arginine/ornithine transport system ATPase from Mycobacterium… · the same entry in another collection · chain A against A, TM-score 1.00

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Every structure of UniProt P63577
Elsewhere: RCSB PDB 3MD0 · PDBe 3MD0 · UniProt P63577

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