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Crystal structure of drosophila BETA1,4-galactosyltransferase-7

Analyse Crystal structure of drosophila BETA1,4-galactosyltransferase-7 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3LW6
Type: protein
Length: 241 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Beta-4-galactosyltransferase 7
EC: 2.4.1.-, 2.4.1.133
UniProt: Q9VBZ9
Ligands: UDP, MN
Pockets: 2 · best druggability 0.77

Structure

x-ray diffraction · 1 distinct chain · 23% helix, 24% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Beta-4-galactosyltransferase 7 (EC 2.4.1.-, 2.4.1.133)	protein	241	23% helix, 24% strand	Q9VBZ9

Ligands and binding sites

UDP · Uridine-5'-diphosphate · ligand · chains A
MN · Manganese (II) ion · metal · chains A
MPD · (4S)-2-methyl-2,4-pentanediol · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	330	0.77	0.88	36	UDP, MPD, MN
2	120	0.54	0.82	22	empty

Modifications

Observed in the structure: 2 disulfide (disulfide).

Compared structures

3LW6 · Crystal Structure of Drosophila beta1,4-galactosyltransferase-7 · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9VBZ9
Elsewhere: RCSB PDB 3LW6 · PDBe 3LW6 · UniProt Q9VBZ9

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