Research workbench
Human mitoneet with 2FE-2S coordinating ligand his 87 replaced with cys
Analyse Human mitoneet with 2FE-2S coordinating ligand his 87 replaced with cys in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3LPQ
- Type
- protein
- Length
- 149 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Cdgsh iron sulfur domain-containing protein 1
- UniProt
- Q9NZ45
- Ligands
- FES
- Pockets
- 1 · best druggability 0.29
Structure
x-ray diffraction · 2 distinct chains · 16% helix, 21% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Cdgsh iron sulfur domain-containing protein 1 | protein | 75 | 16% helix, 21% strand | Q9NZ45 |
| B | Cdgsh iron sulfur domain-containing protein 1 | protein | 74 | 16% helix, 20% strand | Q9NZ45 |
Ligands and binding sites
- FES · Fe2/s2 (inorganic) cluster · ligand · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 54 | 0.29 | 0.75 | 17 | empty |
Interfaces
1 interface between chains.
- A–B · 2156 Ų buried · 47 hydrogen bonds · protein-protein
Compared structures
- 3LPQ · Human MitoNEET with 2Fe-2S Coordinating Ligand His 87 Replaced With Cys · the same entry in another collection · chain A against A, TM-score 1.00
- Q9NZ45 · AlphaFold monomer V2.0 prediction for cdgsh iron-sulfur domain- containing protein 1… · a predicted model of the same protein · chain B against A, TM-score 0.93
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9NZ45
- Elsewhere: RCSB PDB 3LPQ · PDBe 3LPQ · UniProt Q9NZ45
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.