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Structural basis for the binding of an immunodominant peptide from myelin basic protein in different registers by two HLA-DR2 alleles

Analyse Structural basis for the binding of an immunodominant peptide from myelin basic… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1FV1
Type: protein
Length: 775 residues
Chains: 6
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: P01903, Q30154, P02686

Structure

x-ray diffraction · 5 distinct chains.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	—	protein	179	—	P01903
B, E	—	protein	190	—	Q30154
C	—	protein	20	—	P02686
D	—	protein	178	—	P01903
F	—	protein	18	—	P02686

Compared structures

1FV1 · Structural basis for the binding of an immunodominant peptide from myelin basic protein… · the same entry in another collection · chain F against F, TM-score 1.00
P01903 · AlphaFold monomer V2.0 prediction for HLA class II histocompatibility antigen, dr alpha… · a predicted model of the same protein · chain D against A, TM-score 0.96
Q30154 · AlphaFold monomer V2.0 prediction for HLA class II histocompatibility antigen, dr beta 5… · a predicted model of the same protein · chain B against A, TM-score 0.93

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P01903
Every structure of UniProt Q30154
Every structure of UniProt P02686
Elsewhere: RCSB PDB 1FV1 · PDBe 1FV1 · UniProt P01903 · UniProt Q30154 · UniProt P02686

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