Research workbench
A reported archaeal mechanosensitive channel is a structural homolog of marr-like transcriptional regulators
Analyse A reported archaeal mechanosensitive channel is a structural homolog of… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3LFK
- Type
- protein
- Length
- 455 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Marr like protein, TVG0766549
- UniProt
- Q97AP8
- Ligands
- SO4
- Pockets
- 3 · best druggability 0.79
Structure
x-ray diffraction · 4 distinct chains · 52% helix, 18% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Marr like protein, TVG0766549 | protein | 122 | 48% helix, 18% strand | Q97AP8 |
| B | Marr like protein, TVG0766549 | protein | 112 | 54% helix, 19% strand | Q97AP8 |
| C | Marr like protein, TVG0766549 | protein | 111 | 53% helix, 20% strand | Q97AP8 |
| D | Marr like protein, TVG0766549 | protein | 110 | 53% helix, 17% strand | Q97AP8 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1002 | 0.79 | 0.81 | 89 | empty |
| 2 | 85 | 0.41 | 0.78 | 15 | empty |
| 3 | 54 | 0.29 | 0.75 | 20 | empty |
Interfaces
5 interfaces between chains.
- A–D · 913 Ų buried · 11 hydrogen bonds · protein-protein
- A–B · 540 Ų buried · 4 hydrogen bonds · protein-protein
- A–C · 536 Ų buried · 8 hydrogen bonds · protein-protein
- B–C · 318 Ų buried · 3 hydrogen bonds · protein-protein
- B–D · 31 Ų buried · 0 hydrogen bonds · protein-protein
Compared structures
- 3LFK · A reported archaeal mechanosensitive channel is a structural homolog of MarR-like… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q97AP8
- Elsewhere: RCSB PDB 3LFK · PDBe 3LFK · UniProt Q97AP8
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.