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The crystal structure of the tudor domains from FXR1

Analyse The crystal structure of the tudor domains from FXR1 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3KUF
Type: protein
Length: 108 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Fragile X mental retardation syndrome-related protein 1
UniProt: P51114
Pockets: 1 · best druggability 0.35

Structure

x-ray diffraction · 1 distinct chain · 6% helix, 53% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Fragile X mental retardation syndrome-related protein 1	protein	108	6% helix, 53% strand	P51114

Ligands and binding sites

GOL · Glycerol · additive · 5 copies · chains A
DTT · 2,3-dihydroxy-1,4-dithiobutane · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	77	0.35	0.76	16	empty

Compared structures

3KUF · The Crystal Structure of the Tudor Domains from FXR1 · the same entry in another collection · chain A against A, TM-score 1.00
P51114 · AlphaFold monomer V2.0 prediction for fragile X mental retardation syndrome-related… · a predicted model of the same protein · chain A against A, TM-score 0.93

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P51114
Elsewhere: RCSB PDB 3KUF · PDBe 3KUF · UniProt P51114

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