Research workbench
Crystal structure of NADH:FAD oxidoreductase (tftc) - FAD, NADH complex
Analyse Crystal structure of NADH:FAD oxidoreductase (tftc) - FAD, NADH complex in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3K88
- Type
- protein
- Length
- 328 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Chlorophenol-4-monooxygenase component 1
- UniProt
- O87008
- Ligands
- FAD, NAD
- Pockets
- 1 · best druggability 0.73
Structure
x-ray diffraction · 1 distinct chain · 19% helix, 44% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Chlorophenol-4-monooxygenase component 1 | protein | 164 | 19% helix, 44% strand | O87008 |
Ligands and binding sites
- FAD · Flavin-adenine dinucleotide · ligand · 2 copies · chains A, B
- NAD · Nicotinamide-adenine-dinucleotide · ligand · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 860 | 0.73 | 0.77 | 77 | FAD, NAD |
Interfaces
1 interface between chains.
- A–B · 2821 Ų buried · 26 hydrogen bonds · protein-protein
Compared structures
- 3K88 · Crystal structure of NADH:FAD oxidoreductase (TftC) - FAD, NADH complex · the same entry in another collection · chain A against A, TM-score 1.00
- O87008 · AlphaFold monomer V2.0 prediction for NADH:FAD oxidoreductase (O87008) · a predicted model of the same protein · chain A against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O87008
- Elsewhere: RCSB PDB 3K88 · PDBe 3K88 · UniProt O87008
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