Research workbench
Crystal structure analysis of the human IgE-Fc CEPSILON3- CEPSILON4 fragment.
Analyse Crystal structure analysis of the human IgE-Fc CEPSILON3- CEPSILON4 fragment. in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1FP5
- Type
- protein
- Length
- 208 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- IgE heavy chain epsilon-1
- UniProt
- P01854
- Pockets
- 2 · best druggability 0.55
Structure
x-ray diffraction · 1 distinct chain · 11% helix, 47% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | IgE heavy chain epsilon-1 | protein | 208 | 11% helix, 47% strand | P01854 |
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 77 | 0.55 | 0.86 | 17 | empty |
| 2 | 111 | 0.35 | 0.73 | 22 | empty |
Modifications
Observed in the structure: 2 disulfide (disulfide).
Compared structures
- 1FP5 · Crystal structure analysis of the human IgE-Fc CEPSILON3-CEPSILON4 fragment. · the same entry in another collection · chain A against A, TM-score 1.00
- P01854 · AlphaFold monomer V2.0 prediction for immunoglobulin heavy constant epsilon (P01854) · a predicted model of the same protein · chain A against A, TM-score 0.92
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P01854
- Elsewhere: RCSB PDB 1FP5 · PDBe 1FP5 · UniProt P01854
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