Research workbench
Crystal structure of unliganded P. aeruginosa pilt
Analyse Crystal structure of unliganded P. aeruginosa pilt in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3JVU
- Type
- protein
- Length
- 988 residues
- Chains
- 3
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Twitching mobility protein
- UniProt
- P24559
- Ligands
- CL
- Pockets
- 8 · best druggability 0.81
Structure
x-ray diffraction · 3 distinct chains · 37% helix, 28% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Twitching mobility protein | protein | 337 | 37% helix, 28% strand | P24559 |
| B | Twitching mobility protein | protein | 317 | 38% helix, 28% strand | P24559 |
| C | Twitching mobility protein | protein | 334 | 37% helix, 28% strand | P24559 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
8 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1157 | 0.81 | 0.83 | 108 | empty |
| 2 | 841 | 0.81 | 0.84 | 78 | CL |
| 3 | 517 | 0.67 | 0.78 | 75 | CL |
| 4 | 120 | 0.63 | 0.88 | 20 | empty |
| 5 | 51 | 0.39 | 0.81 | 18 | empty |
Interfaces
2 interfaces between chains.
- B–C · 1620 Ų buried · 38 hydrogen bonds · protein-protein
- A–B · 1474 Ų buried · 31 hydrogen bonds · protein-protein
Compared structures
- 3JVU · Crystal structure of unliganded P. aeruginosa PilT · the same entry in another collection · chain A against A, TM-score 1.00
- P24559 · AlphaFold monomer V2.0 prediction for type IV pilus retractation ATPase pilt (P24559) · a predicted model of the same protein · chain C against A, TM-score 0.96
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P24559
- Elsewhere: RCSB PDB 3JVU · PDBe 3JVU · UniProt P24559
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.