Research workbench
Structure of recombinant formate dehydrogenase from arabidopsis thaliana
Analyse Structure of recombinant formate dehydrogenase from arabidopsis thaliana in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3JTM
- Type
- protein
- Length
- 351 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Formate dehydrogenase, mitochondrial
- EC
- 1.2.1.2
- UniProt
- Q9S7E4
- Ligands
- SO4, AZI
- Pockets
- 2 · best druggability 0.67
Structure
x-ray diffraction · 1 distinct chain · 40% helix, 17% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Formate dehydrogenase, mitochondrial (EC 1.2.1.2) | protein | 351 | 40% helix, 17% strand | Q9S7E4 |
Ligands and binding sites
- SO4 · Sulfate ion · ion · 2 copies · chains A
- AZI · Azide ion · ion · 2 copies · chains A
- GOL · Glycerol · additive · 12 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 642 | 0.67 | 0.76 | 65 | GOL |
| 2 | 157 | 0.49 | 0.78 | 29 | GOL, AZI |
Compared structures
- 3JTM · Structure of recombinant formate dehydrogenase from Arabidopsis thaliana · the same entry in another collection · chain A against A, TM-score 1.00
- Q9S7E4 · AlphaFold monomer V2.0 prediction for formate dehydrogenase, CHLOROPLASTIC/MITOCHONDRIAL… · a predicted model of the same protein · chain A against A, TM-score 0.92
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9S7E4
- Elsewhere: RCSB PDB 3JTM · PDBe 3JTM · UniProt Q9S7E4
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