BIML12Y in complex with mcl-1

Structure

x-ray diffraction · 2 distinct chains · 78% helix, 0% strand (DSSP).

Ligands and binding sites

• ZN · Zinc ion · metal · 4 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

1 interface between chains.

• A–B · 1090 Ų buried · 12 hydrogen bonds · protein-protein

Compared structures

• 3IO9 · BimL12Y in complex with Mcl-1 · the same entry in another collection · chain A against A, TM-score 1.00
• Q07820 · AlphaFold monomer V2.0 prediction for induced myeloid leukemia cell differentiation… · a predicted model of the same protein · chain A against A, TM-score 0.95
• P97287 · AlphaFold monomer V2.0 prediction for induced myeloid leukemia cell differentiation… · a predicted model of the same protein · chain A against A, TM-score 0.95
• O43521 · AlphaFold monomer V2.0 prediction for BCL-2-like protein 11 (O43521) · a predicted model of the same protein · chain B against A, TM-score 0.72

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt P97287
• Every structure of UniProt Q07820
• Every structure of UniProt O43521
• Elsewhere: RCSB PDB 3IO9 · PDBe 3IO9 · UniProt P97287 · UniProt Q07820 · UniProt O43521