Crystal structure of the S18Y variant of ubiquitin carboxy terminal hydrolase L1 bound to ubiquitin vinylmethylester.

Structure

x-ray diffraction · 2 distinct chains · 33% helix, 25% strand (DSSP).

Ligands and binding sites

• GVE · Methyl 4-aminobutanoate · ligand · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

1 interface between chains.

• A–B · 1170 Ų buried · 13 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 2 covalent (covalent ligand).

Compared structures

• 3IFW · Crystal structure of the S18Y variant of ubiquitin carboxy terminal hydrolase L1 bound to… · the same entry in another collection · chain A against A, TM-score 1.00
• P09936 · AlphaFold monomer V2.0 prediction for ubiquitin carboxyl-terminal hydrolase isozyme L1… · a predicted model of the same protein · chain A against A, TM-score 0.98

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt P09936
• Every structure of UniProt P62988
• Elsewhere: RCSB PDB 3IFW · PDBe 3IFW · UniProt P09936 · UniProt P62988