Research workbench
Structures of spop-substrate complexes: insights into molecular architectures of btb-CUL3 ubiquitin LIGASES:SPOPMATHX-PUCSBC1_PEP2
Analyse Structures of spop-substrate complexes: insights into molecular architectures… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3HQL
- Type
- protein
- Length
- 281 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Speckle-type poz protein; Puckered
- EC
- 3.1.3.-, 3.1.3.16, 3.1.3.48
- UniProt
- O43791, Q9VHV8
- Ligands
- SO4
Structure
x-ray diffraction · 4 distinct chains · 11% helix, 48% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Speckle-type poz protein | protein | 134 | 12% helix, 49% strand | O43791 |
| B | Speckle-type poz protein | protein | 132 | 12% helix, 50% strand | O43791 |
| C | Puckered (EC 3.1.3.-, 3.1.3.16, 3.1.3.48) | protein | 8 | 0% helix, 13% strand | Q9VHV8 |
| D | Puckered (EC 3.1.3.-, 3.1.3.16, 3.1.3.48) | protein | 7 | 0% helix, 14% strand | Q9VHV8 |
Ligands and binding sites
- SO4 · Sulfate ion · ion · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Interfaces
4 interfaces between chains.
- A–C · 439 Ų buried · 12 hydrogen bonds · protein-protein
- B–D · 408 Ų buried · 11 hydrogen bonds · protein-protein
- A–B · 142 Ų buried · 1 hydrogen bond · protein-protein
- A–D · 45 Ų buried · 0 hydrogen bonds · protein-protein
Compared structures
- 3HQL · Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3… · the same entry in another collection · chain A against A, TM-score 1.00
- O43791 · AlphaFold monomer V2.0 prediction for speckle-type poz protein (O43791) · a predicted model of the same protein · chain B against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O43791
- Every structure of UniProt Q9VHV8
- Elsewhere: RCSB PDB 3HQL · PDBe 3HQL · UniProt O43791 · UniProt Q9VHV8
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