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Crystal structure of human 11-beta-hydroxysteroid-dehydrogenase bound to an ortho-chlro-sulfonyl-piperazine inhibitor

Analyse Crystal structure of human 11-beta-hydroxysteroid-dehydrogenase bound to an… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
3H6K
Type
protein
Length
1,037 residues
Chains
4
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt
P28845

Structure

x-ray diffraction · 4 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
A—protein260—P28845
B—protein261—P28845
C—protein260—P28845
D—protein256—P28845

Compared structures

  • 3H6K · Crystal Structure of Human 11-beta-hydroxysteroid-dehydrogenase Bound to an… · the same entry in another collection · chain D against D, TM-score 1.00
  • P28845 · AlphaFold monomer V2.0 prediction for corticosteroid 11-beta- dehydrogenase isozyme 1… · a predicted model of the same protein · chain A against A, TM-score 1.00

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