Research workbench
TOXIN
Analyse TOXIN in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1FGB
- Type
- protein
- Length
- 515 residues
- Chains
- 5
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Cholera toxin B subunit pentamer
- UniProt
- P01556
- Pockets
- 4 · best druggability 0.73
Structure
x-ray diffraction · 1 distinct chain · 22% helix, 36% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| D, E, F, G, H | Cholera toxin B subunit pentamer | protein | 103 | 22% helix, 36% strand | P01556 |
Pockets
4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 869 | 0.73 | 0.77 | 53 | empty |
| 2 | 50 | 0.41 | 0.83 | 17 | empty |
| 3 | 54 | 0.37 | 0.80 | 16 | empty |
| 4 | 50 | 0.36 | 0.80 | 12 | empty |
Interfaces
5 interfaces between chains.
- E–F · 1322 Ų buried · 27 hydrogen bonds · protein-protein
- D–H · 1311 Ų buried · 23 hydrogen bonds · protein-protein
- D–E · 1258 Ų buried · 24 hydrogen bonds · protein-protein
- G–H · 1256 Ų buried · 29 hydrogen bonds · protein-protein
- F–G · 1236 Ų buried · 27 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 5 disulfide (disulfide).
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P01556
- Elsewhere: RCSB PDB 1FGB · PDBe 1FGB · UniProt P01556
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.