Chromodomain of CHP1 in complex with histone H3K9ME3 peptide

Structure

x-ray diffraction · 2 distinct chains · 26% helix, 44% strand (DSSP).

Ligands and binding sites

• ZN · Zinc ion · metal · 4 copies · chains A
• ACY · Acetic acid · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

1 interface between chains.

• A–P · 653 Ų buried · 19 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 1 modified (methylation).

Compared structures

• 3G7L · Chromodomain of Chp1 in complex with Histone H3K9me3 peptide · the same entry in another collection · chain A against A, TM-score 1.00
• Q10103 · AlphaFold monomer V2.0 prediction for chromo domain-containing protein 1 (Q10103) · a predicted model of the same protein · chain A against A, TM-score 0.89
• P09988 · AlphaFold monomer V2.0 prediction for histone H3.1/H3.2 (P09988) · a predicted model of the same protein · chain P against A, TM-score 0.49

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt Q10103
• Every structure of UniProt P09988
• Elsewhere: RCSB PDB 3G7L · PDBe 3G7L · UniProt Q10103 · UniProt P09988