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The crystal structure of villin domain 6

Analyse The crystal structure of villin domain 6 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3FG7
Type: protein
Length: 212 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Villin-1
UniProt: P09327
Pockets: 2 · best druggability 0.50

Structure

x-ray diffraction · 1 distinct chain · 23% helix, 24% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Villin-1	protein	106	23% helix, 24% strand	P09327

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	240	0.50	0.74	31	empty
2	140	0.46	0.77	26	empty

Interfaces

1 interface between chains.

A–B · 520 Å² buried · 14 hydrogen bonds · protein-protein

Compared structures

3FG7 · The crystal structure of villin domain 6 · the same entry in another collection · chain A against A, TM-score 1.00
P09327 · AlphaFold monomer V2.0 prediction for villin-1 (P09327) · a predicted model of the same protein · chain A against A, TM-score 0.92

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P09327
Elsewhere: RCSB PDB 3FG7 · PDBe 3FG7 · UniProt P09327

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