MolNFT v1 · #496410 · protein

AlphaFold monomer V2.0 prediction for villin-1 (P09327)

P09327: “AlphaFold monomer V2.0 prediction for villin-1 (P09327)”. 13 pockets (best druggability 0.78). MolNFT v1 #496410 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: P09327
Type: protein
Length: 827 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0xF7cDBaE186D2224E9541810F108A2F47B9C78AD3
Molecule: Villin-1
UniProt: P09327
Pockets: 13 · best druggability 0.78

Structure

1 distinct chain · 30% helix, 25% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Villin-1	protein	827	30% helix, 25% strand	P09327

Pockets

13 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	374	0.78	0.87	35	empty
2	298	0.71	0.85	45	empty
3	113	0.64	0.89	22	empty
4	154	0.63	0.86	33	empty
5	116	0.60	0.86	22	empty

Compared structures

3FG7 · The crystal structure of villin domain 6 · an experimental structure of the same protein · chain A against A, TM-score 0.13
3FG7 · The crystal structure of villin domain 6 · an experimental structure of the same protein · chain A against A, TM-score 0.13
1UNC · Solution structure of the human villin C-terminal headpiece subdomain · an experimental structure of the same protein · chain A against A, TM-score 0.04
1UNC · Solution structure of the human villin C-terminal headpiece subdomain · an experimental structure of the same protein · chain A against A, TM-score 0.04

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P09327
Elsewhere: UniProt P09327 · AlphaFold DB P09327

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.