Research workbench
Structure of a putative N-acetyltransferase (TA0374) in complex with acetyl-CoA from thermoplasma acidophilum
Analyse Structure of a putative N-acetyltransferase (TA0374) in complex with acetyl-CoA… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3F0A
- Type
- protein
- Length
- 159 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- N-acetyltransferase
- UniProt
- Q9HL57
- Ligands
- ACO, NI, CL
- Pockets
- 1 · best druggability 0.70
Structure
x-ray diffraction · 1 distinct chain · 43% helix, 33% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | N-acetyltransferase | protein | 159 | 43% helix, 33% strand | Q9HL57 |
Ligands and binding sites
- ACO · Acetyl coenzyme *A · ligand · chains A
- NI · Nickel (II) ion · metal · chains A
- CL · Chloride ion · ion · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 352 | 0.70 | 0.82 | 39 | CL, ACO |
Modifications
Observed in the structure: 3 modified (engineered).
Compared structures
- 3F0A · Structure of a putative n-acetyltransferase (ta0374) in complex with acetyl-coa from… · the same entry in another collection · chain A against A, TM-score 1.00
- Q9HL57 · AlphaFold monomer V2.0 prediction for spermidine N(1)-acetyltransferase (Q9HL57) · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9HL57
- Elsewhere: RCSB PDB 3F0A · PDBe 3F0A · UniProt Q9HL57
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