Research workbench

Lipoxygenase-1 (soybean) at 100K, new refinement

Analyse Lipoxygenase-1 (soybean) at 100K, new refinement in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1F8N
Type: protein
Length: 818 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Lipoxygenase-1
EC: 1.13.11.12
UniProt: P08170
Ligands: FE2
Pockets: 15 · best druggability 0.83

Structure

x-ray diffraction · 1 distinct chain · 42% helix, 15% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Lipoxygenase-1 (EC 1.13.11.12)	protein	818	42% helix, 15% strand	P08170

Ligands and binding sites

FE2 · Fe (II) ion · metal · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

15 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	739	0.83	0.86	63	empty
2	74	0.76	0.99	21	empty
3	419	0.70	0.82	43	empty
4	218	0.50	0.76	31	empty
5	206	0.49	0.75	29	empty

Compared structures

1F8N · Lipoxygenase-1 (soybean) at 100K, new refinement · the same entry in another collection · chain A against A, TM-score 1.00
P08170 · AlphaFold monomer V2.0 prediction for seed linoleate 13S-lipoxygenase-1 (P08170) · a predicted model of the same protein · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P08170
Elsewhere: RCSB PDB 1F8N · PDBe 1F8N · UniProt P08170

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.