Research workbench
The crystal structure of C2B, a fragment of complement component C2 produced during C3-convertase formation
Analyse The crystal structure of C2B, a fragment of complement component C2 produced… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3ERB
- Type
- protein
- Length
- 188 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Complement C2
- EC
- 3.4.21.43
- UniProt
- P06681
- Pockets
- 2 · best druggability 0.44
Structure
x-ray diffraction · 1 distinct chain · 3% helix, 38% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Complement C2 (EC 3.4.21.43) | protein | 188 | 3% helix, 38% strand | P06681 |
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 56 | 0.44 | 0.83 | 15 | empty |
| 2 | 139 | 0.42 | 0.75 | 25 | empty |
Modifications
Observed in the structure: 6 disulfide (disulfide).
Compared structures
- 3ERB · The Crystal Structure of C2b, a Fragment of Complement Component C2 produced during… · the same entry in another collection · chain A against A, TM-score 1.00
- P06681 · AlphaFold monomer V2.0 prediction for complement C2 (P06681) · a predicted model of the same protein · chain A against A, TM-score 0.91
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P06681
- Elsewhere: RCSB PDB 3ERB · PDBe 3ERB · UniProt P06681
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