UniProt P06681
Complement C2b fragment (P06681)
Complement C2b fragment (UniProt P06681): 12 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 8 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P06681
- Protein
- Complement C2b fragment
- Experimental structures
- 12
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 8 · 1 record with a druggable one
Structures
13 records of P06681 in the MolNFT archive: 12 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2I6Q | Complement component C2a | x-ray diffraction | A | — | — |
| 2I6Q | Complement component C2A | x-ray diffraction | A | — | — |
| 2I6S | Complement component C2a | x-ray diffraction | A | — | — |
| 2I6S | Complement component C2A | x-ray diffraction | A | — | — |
| 2ODP | Complement component C2a, the catalytic fragment of C3- and C5-convertase of human complement | x-ray diffraction | A | — | — |
| 2ODP | Complement component C2A, the catalytic fragment of C3- and C5- convertase of human complement | x-ray diffraction | A | — | — |
| 2ODQ | Complement component C2a, the catalytic fragment of C3- and C5-convertase of human complement | x-ray diffraction | A | — | — |
| 2ODQ | Complement component C2A, the catalytic fragment of C3- and C5- convertase of human complement | x-ray diffraction | A | — | — |
| 3ERB | The Crystal Structure of C2b, a Fragment of Complement Component C2 produced during C3-convertase… | x-ray diffraction | A | — | — |
| 3ERB | The crystal structure of C2B, a fragment of complement component C2 produced during C3-convertase… | x-ray diffraction | A | — | — |
| 8ACF | Structure of the argX-117 in complex with a complement C2 fragment at low pH | x-ray diffraction | A | NAG, CA | 4 (best 0.58) |
| 8ACI | Structure of ARG-117 Fab in complex with a fragment of complement C2, neutral pH | x-ray diffraction | A | NAG, FUC, CA | 4 (best 0.48) |
| P06681 | AlphaFold monomer V2.0 prediction for complement C2 (P06681) | predicted | A | — | — |
Ligands
Experiment against prediction
- 2I6Q chain A against the predicted model P06681: TM-score 0.99, RMSD 0.58 Å
- 2I6Q chain A against the predicted model P06681: TM-score 0.99, RMSD 0.58 Å
- 2ODQ chain A against the predicted model P06681: TM-score 0.99, RMSD 0.66 Å
- 2ODQ chain A against the predicted model P06681: TM-score 0.99, RMSD 0.66 Å
- 2ODP chain A against the predicted model P06681: TM-score 0.99, RMSD 0.67 Å
- 2ODP chain A against the predicted model P06681: TM-score 0.99, RMSD 0.67 Å
- 2I6S chain A against the predicted model P06681: TM-score 0.98, RMSD 1.11 Å
- 2I6S chain A against the predicted model P06681: TM-score 0.98, RMSD 1.11 Å
- 8ACI chain A against the predicted model P06681: TM-score 0.96, RMSD 0.96 Å
- 8ACF chain A against the predicted model P06681: TM-score 0.95, RMSD 1.03 Å
Elsewhere
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