Research workbench
Crystal structure of human CGI121
Analyse Crystal structure of human CGI121 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3ENP
- Type
- protein
- Length
- 344 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- TP53RK-binding protein
- UniProt
- Q9Y3C4
- Pockets
- 5 · best druggability 0.79
Structure
x-ray diffraction · 2 distinct chains · 45% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | TP53RK-binding protein | protein | 172 | 45% helix, 16% strand | Q9Y3C4 |
| B | TP53RK-binding protein | protein | 172 | 46% helix, 15% strand | Q9Y3C4 |
Pockets
5 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 595 | 0.79 | 0.85 | 43 | empty |
| 2 | 112 | 0.44 | 0.78 | 17 | empty |
| 3 | 112 | 0.42 | 0.77 | 18 | empty |
| 4 | 64 | 0.37 | 0.78 | 17 | empty |
| 5 | 76 | 0.34 | 0.75 | 22 | empty |
Interfaces
1 interface between chains.
- A–B · 749 Ų buried · 3 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 10 modified, 1 disulfide (engineered, disulfide).
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9Y3C4
- Elsewhere: RCSB PDB 3ENP · PDBe 3ENP · UniProt Q9Y3C4
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.