UniProt Q9Y3C4
EKC/KEOPS complex subunit TPRKB (Q9Y3C4)
EKC/KEOPS complex subunit TPRKB (UniProt Q9Y3C4): 8 experimental structures and 1 predicted model on GenesisL1, 44 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9Y3C4
- Protein
- EKC/KEOPS complex subunit TPRKB
- Experimental structures
- 8
- Predicted models
- 1
- Pockets
- 44 · 4 records with a druggable one
Structures
9 records of Q9Y3C4 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3ENP | Crystal structure of human cgi121 | x-ray diffraction | A, B | — | — |
| 3ENP | Crystal structure of human CGI121 | x-ray diffraction | A, B | — | — |
| 6WQX | Human PRPK-TPRKB complex | x-ray diffraction | B, A | — | 9 (best 0.58) |
| 6WQX | Human prpk-tprkb complex | x-ray diffraction | B, A | — | — |
| 7SZA | Crystal Structure Analysis of human PRPK complex with a compound | x-ray diffraction | B, D | — | 9 (best 0.50) |
| 7SZB | Crystal Structure Analysis of human PRPK complex with a compound | x-ray diffraction | B, D | — | 8 (best 0.43) |
| 7SZC | Crystal Structure Analysis of human PRPK complex with a compound | x-ray diffraction | B, D | — | 8 (best 0.68) |
| 7SZD | Crystal Structure Analysis of human PRPK complex with a compound | x-ray diffraction | B, D | — | 9 (best 0.52) |
| Q9Y3C4 | AlphaFold monomer V2.0 prediction for EKC/KEOPS complex subunit tprkb (Q9Y3C4) | predicted | A | — | 1 (best 0.53) |
Experiment against prediction
- 6WQX chain B against the predicted model Q9Y3C4: TM-score 0.98, RMSD 0.62 Å
- 6WQX chain B against the predicted model Q9Y3C4: TM-score 0.98, RMSD 0.62 Å
- 7SZB chain D against the predicted model Q9Y3C4: TM-score 0.97, RMSD 0.62 Å
- 7SZA chain D against the predicted model Q9Y3C4: TM-score 0.98, RMSD 0.63 Å
- 7SZA chain B against the predicted model Q9Y3C4: TM-score 0.97, RMSD 0.64 Å
- 7SZB chain B against the predicted model Q9Y3C4: TM-score 0.97, RMSD 0.63 Å
- 7SZC chain D against the predicted model Q9Y3C4: TM-score 0.98, RMSD 0.67 Å
- 7SZD chain B against the predicted model Q9Y3C4: TM-score 0.98, RMSD 0.64 Å
- 7SZC chain B against the predicted model Q9Y3C4: TM-score 0.98, RMSD 0.54 Å
- 3ENP chain B against the predicted model Q9Y3C4: TM-score 0.95, RMSD 1.43 Å
Elsewhere
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