Research workbench

Crystal structure of human SPLA/RYANODINE receptor domain and socs box containing 2 (SPSB2) in complex with a 20-residue vasa peptide

Analyse Crystal structure of human SPLA/RYANODINE receptor domain and socs box… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3EMW
Type: protein
Length: 207 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Spry domain-containing socs box protein 2; Peptide (vasa)
UniProt: Q99619

Structure

x-ray diffraction · 2 distinct chains · 11% helix, 39% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Spry domain-containing socs box protein 2	protein	200	11% helix, 40% strand	Q99619
B	Peptide (vasa)	protein	7	0% helix, 14% strand	—

Ligands and binding sites

EDO · 1,2-ethanediol · additive · 4 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

1 interface between chains.

A–B · 368 Å² buried · 15 hydrogen bonds · protein-protein

Compared structures

3EMW · Crystal Structure of human splA/ryanodine receptor domain and SOCS box containing 2… · the same entry in another collection · chain A against A, TM-score 1.00
Q99619 · AlphaFold monomer V2.0 prediction for spry domain-containing socs box protein 2 (Q99619) · a predicted model of the same protein · chain A against A, TM-score 0.97

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q99619
Elsewhere: RCSB PDB 3EMW · PDBe 3EMW · UniProt Q99619

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.