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Microtubule-associated protein 1 light chain 3 alpha isoform a (MAP1ALC3)

Analyse Microtubule-associated protein 1 light chain 3 alpha isoform a (MAP1ALC3) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3ECI
Type: protein
Length: 224 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Microtubule-associated protein 1 light chain 3 alpha
UniProt: Q9H492
Pockets: 2 · best druggability 0.51

Structure

x-ray diffraction · 1 distinct chain · 34% helix, 25% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Microtubule-associated protein 1 light chain 3 alpha	protein	112	34% helix, 25% strand	Q9H492

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	246	0.51	0.75	34	empty
2	50	0.32	0.77	13	empty

Interfaces

1 interface between chains.

A–B · 260 Å² buried · 3 hydrogen bonds · protein-protein

Compared structures

3ECI · Microtubule-associated protein 1 light chain 3 alpha isoform A (MAP1ALC3) · the same entry in another collection · chain A against A, TM-score 1.00
Q9H492 · AlphaFold monomer V2.0 prediction for microtubule-associated proteins 1A/1B light chain… · a predicted model of the same protein · chain A against A, TM-score 0.97

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9H492
Elsewhere: RCSB PDB 3ECI · PDBe 3ECI · UniProt Q9H492

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