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UniProt Q9H492

Microtubule-associated proteins 1A/1B light chain 3A (Q9H492)

Microtubule-associated proteins 1A/1B light chain 3A (UniProt Q9H492): 16 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 10 pockets. Binding sites, druggability and experiment against prediction…

UniProt
Q9H492
Protein
Microtubule-associated proteins 1A/1B light chain 3A
Experimental structures
16
Predicted models
1
Ligands
4
Pockets
10 · 2 records with a druggable one

Structures

17 records of Q9H492 in the MolNFT archive: 16 experimental, 1 predicted.

EntryTitleMethodChainsLigandsPockets
3ECIMicrotubule-associated protein 1 light chain 3 alpha isoform A (MAP1ALC3)x-ray diffractionA, B——
3ECIMicrotubule-associated protein 1 light chain 3 alpha isoform a (MAP1ALC3)x-ray diffractionA, B——
3WALCrystal structure of human LC3A_2-121x-ray diffractionA——
3WALCrystal structure of human LC3A_2-121x-ray diffractionA——
3WANCrystal structure of Atg13 LIR-fused human LC3A_2-121x-ray diffractionA, B——
3WANCrystal structure of ATG13 lir-fused human LC3A_2-121x-ray diffractionA, B——
4ZDVCrystal structure of LC3 in complex with FAM134B lirx-ray diffractionA——
5CX3Crystal structure of FYCO1 LIR in complex with LC3Ax-ray diffractionA, B, C, D—7 (best 0.63)
5CX3Crystal structure of FYCO1 lir in complex with LC3Ax-ray diffractionA, B, C, D——
5DPRCrystal structure of PLEKHM1 LIR-fused human LC3A_2-121x-ray diffractionA, B, C, D——
5DPRCrystal structure of PLEKHM1 lir-fused human LC3A_2-121x-ray diffractionA, B, C, D——
6TBELC3A in complex with (3R,4S,5R,6R)-5-hydroxy-6-((4-hydroxy-3-(4…x-ray diffractionANOV—
7R9WLC3A in complex with fragment 1-1x-ray diffractionAJO4—
7R9ZLC3A in complex with fragment 2-3x-ray diffractionA2LZ—
7RA0LC3A in complex with fragment 2-10x-ray diffractionA2JI—
8T2LCrystal structure of LC3A in complex with the LIR of NSs4x-ray diffractionA, B—3 (best 0.54)
Q9H492AlphaFold monomer V2.0 prediction for microtubule-associated proteins 1A/1B light chain 3A (Q9H492)predictedA——

Ligands

  • 2JI · (5-ethyl-2-methyl-1H-indol-3-yl)acetic acid · in 1 record
  • 2LZ · (5-fluoro-1H-indol-3-yl)acetic acid · in 1 record
  • JO4 · 4-phenoxybenzoic acid · in 1 record
  • NOV · Novobiocin · in 1 record

Experiment against prediction

Elsewhere

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