Research workbench
Crystal structure of the beta-finger domain of yeast PRP8
Analyse Crystal structure of the beta-finger domain of yeast PRP8 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3E66
- Type
- protein
- Length
- 510 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- PRP8
- UniProt
- P33334
- Pockets
- 7 · best druggability 0.72
Structure
x-ray diffraction · 1 distinct chain · 47% helix, 18% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | PRP8 | protein | 255 | 47% helix, 18% strand | P33334 |
Pockets
7 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 544 | 0.72 | 0.80 | 53 | empty |
| 2 | 386 | 0.69 | 0.81 | 41 | empty |
| 3 | 163 | 0.56 | 0.81 | 24 | empty |
| 4 | 54 | 0.49 | 0.85 | 12 | empty |
| 5 | 110 | 0.48 | 0.80 | 18 | empty |
Interfaces
1 interface between chains.
- A–B · 1001 Ų buried · 6 hydrogen bonds · protein-protein
Compared structures
- 3E66 · Crystal structure of the beta-finger domain of yeast Prp8 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P33334
- Elsewhere: RCSB PDB 3E66 · PDBe 3E66 · UniProt P33334
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.