P3(2) crystal structure of ALA2ILE2-6, a version of rop with a repacked hydrophobic core and a new fold.

Structure

x-ray diffraction · 6 distinct chains · 91% helix, 0% strand (DSSP).

Ligands and binding sites

• CA · Calcium ion · metal · 6 copies · chains A, C, E

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

6 interfaces between chains.

• C–D · 1415 Ų buried · 13 hydrogen bonds · protein-protein
• A–B · 1379 Ų buried · 8 hydrogen bonds · protein-protein
• E–F · 1307 Ų buried · 14 hydrogen bonds · protein-protein
• B–F · 190 Ų buried · 8 hydrogen bonds · protein-protein
• D–E · 78 Ų buried · 1 hydrogen bond · protein-protein

Compared structures

• 1F4M · P3(2) crystal structure of ALA2ILE2-6, a version of rop with a repacked hydrophobic core… · the same entry in another collection · chain F against F, TM-score 1.00
• P03051 · AlphaFold monomer V2.0 prediction for regulatory protein rop (P03051) · a predicted model of the same protein · chain F against A, TM-score 0.87

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt P03051
• Elsewhere: RCSB PDB 1F4M · PDBe 1F4M · UniProt P03051