Complex structure of GABA type a receptor associated protein and its binding epitope on calreticulin

Structure

x-ray diffraction · 2 distinct chains · 31% helix, 21% strand (DSSP).

Ligands and binding sites

• ZN · Zinc ion · metal · chains A
• NH2 · Amino group · ion · chains B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

1 interface between chains.

• A–B · 573 Ų buried · 10 hydrogen bonds · protein-protein

Compared structures

• 3DOW · Complex structure of GABA type A receptor associated protein and its binding epitope on… · the same entry in another collection · chain A against A, TM-score 1.00
• O95166 · AlphaFold monomer V2.0 prediction for gamma-aminobutyric acid receptor-associated protein… · a predicted model of the same protein · chain A against A, TM-score 0.95
• P27797 · AlphaFold monomer V2.0 prediction for calreticulin (P27797) · a predicted model of the same protein · chain B against A, TM-score 0.62

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt O95166
• Every structure of UniProt P27797
• Elsewhere: RCSB PDB 3DOW · PDBe 3DOW · UniProt O95166 · UniProt P27797