Research workbench
Crystal structure of isolated C2 domain of the methionine uptake transporter
Analyse Crystal structure of isolated C2 domain of the methionine uptake transporter in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3DHX
- Type
- protein
- Length
- 198 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Methionine import ATP-binding protein metn
- EC
- 3.6.3.-
- UniProt
- P30750
- Ligands
- IOD
- Pockets
- 2 · best druggability 0.32
Structure
x-ray diffraction · 1 distinct chain · 27% helix, 45% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Methionine import ATP-binding protein metn (EC 3.6.3.-) | protein | 99 | 27% helix, 45% strand | P30750 |
Ligands and binding sites
- IOD · Iodide ion · ion · 12 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 58 | 0.32 | 0.76 | 14 | empty |
| 2 | 50 | 0.30 | 0.76 | 17 | empty |
Interfaces
1 interface between chains.
- A–B · 1238 Ų buried · 28 hydrogen bonds · protein-protein
Compared structures
- 3DHX · Crystal structure of isolated C2 domain of the methionine uptake transporter · the same entry in another collection · chain A against A, TM-score 1.00
- P30750 · AlphaFold monomer V2.0 prediction for methionine import ATP-binding protein metn (P30750) · a predicted model of the same protein · chain A against A, TM-score 0.89
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P30750
- Elsewhere: RCSB PDB 3DHX · PDBe 3DHX · UniProt P30750
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