Research workbench
Structural analysis of a holo enzyme complex of mouse dihydrofolate reductase with NADPH and a ternary complex with the potent and selective inhibitor 2.4-diamino-6-(-2'-HYDROXYDIBENZ[B,F]AZEPIN-5- YL)METHYLPTERIDINE
Analyse Structural analysis of a holo enzyme complex of mouse dihydrofolate reductase… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3D84
- Type
- protein
- Length
- 186 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P00375
Structure
x-ray diffraction · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| X | — | protein | 186 | — | P00375 |
Compared structures
- 3D84 · Structural Analysis of a Holo Enzyme Complex of Mouse Dihydrofolate Reductase with NADPH… · the same entry in another collection · chain X against X, TM-score 1.00
- P00375 · AlphaFold monomer V2.0 prediction for dihydrofolate reductase (P00375) · a predicted model of the same protein · chain X against A, TM-score 0.97
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P00375
- Elsewhere: RCSB PDB 3D84 · PDBe 3D84 · UniProt P00375
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