Research workbench

Cleaved antichymotrypsin A347R

Analyse Cleaved antichymotrypsin A347R in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3CAA
Type: protein
Length: 366 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Antichymotrypsin
UniProt: P01011
Pockets: 3 · best druggability 0.61

Structure

x-ray diffraction · 2 distinct chains · 29% helix, 38% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Antichymotrypsin	protein	334	31% helix, 37% strand	P01011
B	Antichymotrypsin	protein	32	0% helix, 47% strand	P01011

Pockets

3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	184	0.61	0.82	24	empty
2	86	0.45	0.80	17	empty
3	78	0.34	0.75	16	empty

Interfaces

1 interface between chains.

A–B · 2421 Å² buried · 36 hydrogen bonds · protein-protein

Compared structures

3CAA · Cleaved antichymotrypsin A347R · the same entry in another collection · chain A against A, TM-score 1.00
P01011 · AlphaFold monomer V2.0 prediction for alpha-1-antichymotrypsin (P01011) · a predicted model of the same protein · chain A against A, TM-score 0.93

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P01011
Elsewhere: RCSB PDB 3CAA · PDBe 3CAA · UniProt P01011

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.