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Crystal structure of the C-terminal deleted mutant of the class a carbapenemase kpc-2 at 1.23 ångström

Analyse Crystal structure of the C-terminal deleted mutant of the class a carbapenemase… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3C5A
Type: protein
Length: 264 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Class a carbapenemase kpc-2
UniProt: A8DS27
Pockets: 1 · best druggability 0.32

Structure

x-ray diffraction · 1 distinct chain · 44% helix, 17% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Class a carbapenemase kpc-2	protein	264	44% helix, 17% strand	A8DS27

Ligands and binding sites

CIT · Citric acid · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	86	0.32	0.74	19	CIT

Modifications

Observed in the structure: 1 disulfide (disulfide).

Compared structures

3C5A · Crystal structure of the C-terminal deleted mutant of the class A carbapenemase KPC-2 at… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A8DS27
Elsewhere: RCSB PDB 3C5A · PDBe 3C5A · UniProt A8DS27

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