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Crystal structure of open form of menaquinone-specific isochorismate synthase, menf

Analyse Crystal structure of open form of menaquinone-specific isochorismate synthase… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3BZM
Type: protein
Length: 429 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Menaquinone-specific isochorismate synthase
EC: 5.4.4.2
UniProt: P38051
Pockets: 2 · best druggability 0.69

Structure

x-ray diffraction · 1 distinct chain · 31% helix, 35% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Menaquinone-specific isochorismate synthase (EC 5.4.4.2)	protein	429	31% helix, 35% strand	P38051

Ligands and binding sites

CIT · Citric acid · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	294	0.69	0.84	42	empty
2	80	0.42	0.80	21	empty

Compared structures

3BZM · Crystal Structure of Open form of Menaqui -Specific Isochorismate Synthase, MenF · the same entry in another collection · chain A against A, TM-score 1.00
P38051 · AlphaFold monomer V2.0 prediction for isochorismate synthase menf (P38051) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P38051
Elsewhere: RCSB PDB 3BZM · PDBe 3BZM · UniProt P38051

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