Research workbench
Crystal structure of streptomyces cholesterol oxidase H447Q/E361Q mutant (1.2A)
Analyse Crystal structure of streptomyces cholesterol oxidase H447Q/E361Q mutant (1.2A) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3B6D
- Type
- protein
- Length
- 498 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Cholesterol oxidase
- EC
- 1.1.3.6
- UniProt
- P12676
- Ligands
- FAE, SO4
- Pockets
- 3 · best druggability 0.87
Structure
x-ray diffraction · 1 distinct chain · 29% helix, 24% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Cholesterol oxidase (EC 1.1.3.6) | protein | 498 | 29% helix, 24% strand | P12676 |
Ligands and binding sites
- FAE · Flavin-N7 protonated-adenine dinucleotide · ligand · chains A
- SO4 · Sulfate ion · ion · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 741 | 0.87 | 0.90 | 83 | FAE |
| 2 | 156 | 0.55 | 0.81 | 30 | empty |
| 3 | 74 | 0.31 | 0.74 | 23 | empty |
Compared structures
- 3B6D · Crystal Structure of Streptomyces Cholesterol Oxidase H447Q/E361Q mutant (1.2A) · the same entry in another collection · chain A against A, TM-score 1.00
- P12676 · AlphaFold monomer V2.0 prediction for cholesterol oxidase (P12676) · a predicted model of the same protein · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P12676
- Elsewhere: RCSB PDB 3B6D · PDBe 3B6D · UniProt P12676
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.