Research workbench

Crystal structure of the human SNP PAD4 protein

Analyse Crystal structure of the human SNP PAD4 protein in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3APM
Type: protein
Length: 559 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Protein-arginine deiminase type-4
EC: 3.5.3.15
UniProt: Q9UM07
Pockets: 3 · best druggability 0.73

Structure

x-ray diffraction · 1 distinct chain · 18% helix, 39% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Protein-arginine deiminase type-4 (EC 3.5.3.15)	protein	559	18% helix, 39% strand	Q9UM07

Pockets

3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	481	0.73	0.82	57	empty
2	95	0.50	0.82	24	empty
3	101	0.36	0.74	21	empty

Compared structures

3APM · Crystal structure of the human SNP PAD4 protein · the same entry in another collection · chain A against A, TM-score 1.00
Q9UM07 · AlphaFold monomer V2.0 prediction for protein-arginine deiminase type-4 (Q9UM07) · a predicted model of the same protein · chain A against A, TM-score 0.98

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9UM07
Elsewhere: RCSB PDB 3APM · PDBe 3APM · UniProt Q9UM07

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.