Research workbench
Structure of human REV7 in complex with a human REV3 fragment in a tetragonal crystal
Analyse Structure of human REV7 in complex with a human REV3 fragment in a tetragonal… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3ABE
- Type
- protein
- Length
- 217 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Mitotic spindle assembly checkpoint protein MAD2B; DNA polymerase zeta catalytic subunit
- UniProt
- Q9UI95, O60673
- Pockets
- 1 · best druggability 0.32
Structure
x-ray diffraction · 2 distinct chains · 36% helix, 29% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| C | Mitotic spindle assembly checkpoint protein MAD2B | protein | 196 | 38% helix, 30% strand | Q9UI95 |
| Z | DNA polymerase zeta catalytic subunit | protein | 21 | 24% helix, 19% strand | O60673 |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 57 | 0.32 | 0.76 | 20 | empty |
Interfaces
1 interface between chains.
- C–Z · 1145 Ų buried · 22 hydrogen bonds · protein-protein
Compared structures
- 3ABE · Structure of human REV7 in complex with a human REV3 fragment in a tetragonal crystal · the same entry in another collection · chain C against C, TM-score 1.00
- Q9UI95 · AlphaFold monomer V2.0 prediction for mitotic spindle assembly checkpoint protein MAD2B… · a predicted model of the same protein · chain C against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9UI95
- Every structure of UniProt O60673
- Elsewhere: RCSB PDB 3ABE · PDBe 3ABE · UniProt Q9UI95 · UniProt O60673
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.