Research workbench
Crystal structure of complex between sa-subtilisin and tk-propeptide with deletion of the five C-terminal residues
Analyse Crystal structure of complex between sa-subtilisin and tk-propeptide with… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3A3O
- Type
- protein
- Length
- 378 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Tk-subtilisin
- EC
- 3.4.21.-
- UniProt
- P58502
- Ligands
- CA, ZN
- Pockets
- 1 · best druggability 0.43
Structure
x-ray diffraction · 2 distinct chains · 29% helix, 22% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Tk-subtilisin (EC 3.4.21.-) | protein | 318 | 29% helix, 19% strand | P58502 |
| B | Tk-subtilisin | protein | 60 | 30% helix, 40% strand | P58502 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 111 | 0.43 | 0.77 | 29 | empty |
Interfaces
1 interface between chains.
- A–B · 784 Ų buried · 15 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 1 disulfide (disulfide).
Compared structures
- 3A3O · Crystal structure of complex between SA-subtilisin and Tk-propeptide with deletion of the… · the same entry in another collection · chain A against A, TM-score 1.00
- P58502 · AlphaFold monomer V2.0 prediction for tk-subtilisin (P58502) · a predicted model of the same protein · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P58502
- Elsewhere: RCSB PDB 3A3O · PDBe 3A3O · UniProt P58502
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.