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A 1.3 a resolution crystal structure of the HIV-1 trans- activation response region RNA stem reveals a metal ion- dependent bulge conformation

Analyse A 1.3 a resolution crystal structure of the HIV-1 trans- activation response… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
397D
Type
RNA
Length
27 nucleotides
Chains
2
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
RNA (5'- R(*GP*GP*CP*CP*AP*GP*AP*UP*CP*UP*GP*AP*GP*CP*G)-3'); RNA…
Ligands
CA

Structure

x-ray diffraction · 2 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
ARNA (5'- R(*GP*GP*CP*CP*AP*GP*AP*UP*CP*UP*GP*AP*GP*CP*G)-3')rna15——
BRNA (5'-R(*GP*CP*UP*CP*UP*CP*UP*GP*GP*CP*CP*C)- 3')rna12——

Ligands and binding sites

  • CA · Calcium ion · metal · 4 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

1 interface between chains.

  • A–B · 591 Ų buried · 56 hydrogen bonds · nucleic-nucleic

Compared structures

  • 397D · A 1.3 a resolution crystal structure of the HIV-1 trans-activation response region RNA… · the same entry in another collection · chain A against A, TM-score 1.00

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