Research workbench
Crystal structure of D157A mutant of pseudomonas sp. MIS38 lipase
Analyse Crystal structure of D157A mutant of pseudomonas sp. MIS38 lipase in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2ZJ7
- Type
- protein
- Length
- 616 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Lipase
- EC
- 3.1.1.3
- UniProt
- Q9RBY1
- Ligands
- CA, ZN
- Pockets
- 5 · best druggability 0.65
Structure
x-ray diffraction · 1 distinct chain · 26% helix, 26% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Lipase (EC 3.1.1.3) | protein | 616 | 26% helix, 26% strand | Q9RBY1 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
5 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 98 | 0.65 | 0.90 | 23 | empty |
| 2 | 275 | 0.62 | 0.80 | 48 | empty |
| 3 | 79 | 0.54 | 0.86 | 25 | empty |
| 4 | 204 | 0.53 | 0.77 | 32 | empty |
| 5 | 66 | 0.48 | 0.84 | 21 | empty |
Compared structures
- 2ZJ7 · Crystal structure of D157A mutant of Pseudomonas sp. MIS38 lipase · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9RBY1
- Elsewhere: RCSB PDB 2ZJ7 · PDBe 2ZJ7 · UniProt Q9RBY1
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